William J. Steinbach, M.D. Pediatrician
Primary Appointment Location
Arkansas Children’s Hospital
1 Children's Way
Little Rock, AR 72202
- Area of Expertise
- Pediatric Care
- Accepting New Patients
- Patient Type
- Children and Adolescents
About Dr. Steinbach
Dr. Steinbach is the single researcher in the world whose expertise in pediatric invasive fungal infections covers the spectrum from novel molecular pathogenesis contributions to FDA approval of pediatric diagnostic biomarkers, to redefining epidemiology for the field, to leading the international consortium performing clinical trials to develop new evidence-based treatment guidelines. Every national or international guideline or textbook related to pediatric invasive fungal infection diagnosis or management in the last decade has been lead or co-developed by him. His clinical expertise is in infections in immunocompromised children, specifically those with cancer or following transplantation.
Dr. Steinbach's Academic Background
William J. Steinbach, M.D. is Robert H. Fiser, Jr. MD Endowed Chair in Pediatrics, Chair of Pediatrics and Associate Dean for Child Health at UAMS, and the Pediatrician-in-Chief at Arkansas Children’s since January 2022. Before assuming UAMS Pediatrics’s leadership, he was the Samuel L. Katz Distinguished Professor of Pediatrics and Vice-Chair of Research at Duke University.
- Department Chair
- American Academy of Pediatrics - Committee on Infectious Diseases (Red Book Committee)
- Pediatric Infectious Diseases Society
- American Pediatric Society
- Alpha Omega Alpha
- American Association for the Advancement of Science
- American Association of Microbiology
- American Society for Clinical Investigation
- Association of American Physicians
- American Federation for Medical Research
- Infectious Diseases Society of America
Dr. Steinbach's Research
For the last 20 years, Dr. Steinbach has led an NIH-funded multidisciplinary clinical care and research program supporting immunosuppressed children. His molecular, translational, and clinical research focuses on the pathogenesis, diagnosis and treatment of invasive fungal infections and spans broader efforts with all infections in immunocompromised patients. His laboratory centers on the fungus Aspergillus fumigatus to understand the molecular mechanisms of cellular signal transduction in disease, develop novel fungal-specific molecular targets as therapeutics, devise new diagnostic assays, and conduct phase I-IV clinical trials in children.
Dr. Steinbach first became interested in invasive fungal infections during his time as a pediatric resident at Stanford University where he saw the immense morbidity and mortality associated with these conditions. As a pediatric resident, he was named one of 8 fellows from all pediatric specialties to be accepted into the prestigious NICHD-funded Pediatric Scientist Development Program. During his fellowship in pediatric infectious diseases at Duke University, he was awarded an NIH career development K08 grant to continue his molecular mycology research. Just prior to completing his pediatric infectious diseases fellowship, he completed a three-month sabbatical at the Unité des Aspergillus at the Institut Pasteur studying under Dr. Jean-Paul Latgé, one of the world leaders in Aspergillus biology. Later, in 2007, he completed another three-month sabbatical at the University of Perugia (Italy) under Dr. Luigina Romani, a world leader in fungal immunology.
Dr. Steinbach founded and is the Director of the International Pediatric Fungal Network, a global consortium of 55 sites dedicated to investigating pediatric invasive fungal infections through multi-center cooperative studies that have led to the first pediatric-specific guidelines for these diseases. He has co-edited 14 textbook editions, including Aspergillus fumigatus and Aspergillosis, the two-volume 4,000-page Feigin & Cherry’s Textbook of Pediatric Infectious Diseases, the American Academy of Pediatrics Nelson’s Pediatric Antimicrobial Therapy, and most recently the first textbook in a new subfield: Pediatric Transplant and Oncology Infectious Diseases.
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.