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  1. UAMS Health
  2. Providers
  3. Matthew G. Deneke, M.D.

Matthew G. Deneke, M.D. Gastroenterologist

Primary Appointment Location

Gastroenterology Clinic
4110 Outpatient Circle
Outpatient Center
Suite 3160
Little Rock, AR 72205

Appointment Phone Number
501-603-1900
New and Returning Patients
View Location View All Locations

Overview

Areas of Expertise
Organ Transplantation
Digestive Health
Accepting New Patients
Yes
Patient Type
Adults
Language
English
4.8 out of 5
151 Patient Satisfaction Ratings
26 comments
Matthew G. Deneke, M.D.

Contents

  • Make an Appointment
  • About
  • Academic Background
  • Research
  • Conditions
  • Treatments & Procedures
  • Areas of Expertise
  • Locations
  • Ratings & Reviews

Make an Appointment With Dr. Deneke

New patients can make an appointment by contacting the clinic directly.

Existing patients also have the option of requesting an appointment online through UAMS Health MyChart.

About Dr. Deneke

Clinical Biography

Dr. Deneke initially joined the faculty at UAMS in 2005 as an Assistant Professor of Medicine for the Division of General Internal Medicine. While faculty, he served as Medical Director of the ambulatory teaching clinic for internal medicine residents and as the Associate Practice Director for UAMS Internal Medicine Clinics. After five years, Dr. Deneke stepped down as faculty to pursue additional training in gastroenterology and hepatology. He rejoined the UAMS faculty in the Division of Gastroenterology and Hepatology in 2014. He is currently the program director for the UAMS Gastroenterology Fellowship Program. He is a part of the UAMS Liver Transplant team and also operates the UAMS Fatty Liver Disease Clinic.

His clinical interests include liver disease, with a focus on nonalcoholic fatty liver disease, complications of liver disease, and liver transplantation.

Dr. Deneke's Academic Background

Faculty Appointments

Department of Internal Medicine — Division of Gastroenterology and Hepatology
Assistant Professor

Education and Training

Medical School
University of Arkansas for Medical Sciences
Residency
University of Alabama at Birmingham
Fellowship
University of Arkansas for Medical Sciences
Fellowship
Mayo Clinic
Transplant Hepatology

Professional Certifications

  • American Board of Internal Medicine — Internal Medicine

Dr. Deneke's Research

UAMS Research Profile

Each UAMS faculty member has a research profile page that includes biographical and contact information, a list of their most recent grant activity and a list of their PubMed publications.

View Dr. Deneke's research profile

Conditions Diagnosed or Treated by Dr. Deneke

UAMS Health providers care for a broad range of conditions, some of which may not be listed below.

  • Gastrointestinal Disease
  • Liver Disease

Medical Treatments and Procedures Performed or Prescribed by Dr. Deneke

UAMS Health providers perform and prescribe a broad range of treatments and procedures, some of which may not be listed below.

  • Liver Transplant Surgery

Dr. Deneke's Areas of Expertise

Granddaughter Visiting Grandmother In Hospital Bed For Afternoon Tea

Organ Transplantation

Organ transplants are often life-saving treatments for conditions where an organ has failed or is no longer functioning properly.

View Area of Expertise
Image of little boy having tummy examination by pediatrician at doctor's office.

Digestive Health

With highly skilled and trained specialists and the latest technology, UAMS Health's digestive health services are the most complete in the state.

View Area of Expertise

Locations Where Dr. Deneke Practices

Exterior of Outpatient Center

Gastroenterology Clinic , Primary Location

4110 Outpatient Circle
Outpatient Center
Suite 3160
Little Rock, AR 72205

Appointment Phone Number
501-603-1900
New and Returning Patients
View Location Get Directions
Exterior of Outpatient Center

Liver Transplant Clinic at the UAMS Medical Center

4110 Outpatient Circle
Outpatient Center
Suite 3150
Little Rock, AR 72205

Appointment Phone Number
800-552-8026
New and Returning Patients
View Location Get Directions

Patient Ratings & Reviews

Average Ratings

Likelihood of recommending this provider
4.7 out of 5
Provider discussed treatment options
4.8 out of 5
Provider explained things clearly
4.8 out of 5
Provider included you in decisions
4.8 out of 5
Provider showed concern
4.8 out of 5

Overall: 4.8 out of 5

(151 Ratings, 26 Comments)

Individual Reviews

4 out of 5

Comment

Would recommend this practice with the caveat of the extremely long wait time.My appointment was on a Monday and I understand that this is a busy day, but my appointment time was 2:15 and I left the clinic after 4;30. In fact, the Fellow left the clinic before I did. So, my over two hours in clinic involved 5-10 minutes with the Fellow and less than 5 minutes with the Doctor. I did schedule another appointment, and I requested a day other that Monday or Wednesday--another busy day I was told by the check-out person. However, it appears the Fellow or Doctor, or both, only have Monday appointments. This seemed odd to me and the check-out person.

Date

Sep 11, 2025
3 out of 5

Comment

Fair

Date

Sep 03, 2025
5 out of 5

Comment

[NAME] APRN goes out of her way to help. Smart and very capable. She is genuinely concerned and I truly appreciate all of her help. Dr Deneke is awesome. Love my team!

Date

Aug 29, 2025
5 out of 5

Comment

Willing to bring in another doctor from UAMS for a concurring opinion.

Date

Aug 12, 2025
3.6 out of 5

Comment

I saw a Fellow Dr. [NAME]. Personally, I was not happy with his "bedside manner". He often interrupted my explanations and seemed to be listening to answer versus to hear what I was really saying/concerned about. I personally would rather see Dr. Deneke or someone else at my next visit.

Date

Aug 01, 2025
5 out of 5

Comment

Dr. Deneke is a wonderful, caring doctor

Date

Jul 12, 2025
More Recent Reviews
4 out of 5

Comment

Would recommend this practice with the caveat of the extremely long wait time.My appointment was on a Monday and I understand that this is a busy day, but my appointment time was 2:15 and I left the clinic after 4;30. In fact, the Fellow left the clinic before I did. So, my over two hours in clinic involved 5-10 minutes with the Fellow and less than 5 minutes with the Doctor. I did schedule another appointment, and I requested a day other that Monday or Wednesday--another busy day I was told by the check-out person. However, it appears the Fellow or Doctor, or both, only have Monday appointments. This seemed odd to me and the check-out person.

Date

Sep 11, 2025
3 out of 5

Comment

Fair

Date

Sep 03, 2025
5 out of 5

Comment

[NAME] APRN goes out of her way to help. Smart and very capable. She is genuinely concerned and I truly appreciate all of her help. Dr Deneke is awesome. Love my team!

Date

Aug 29, 2025
5 out of 5

Comment

Willing to bring in another doctor from UAMS for a concurring opinion.

Date

Aug 12, 2025
3.6 out of 5

Comment

I saw a Fellow Dr. [NAME]. Personally, I was not happy with his "bedside manner". He often interrupted my explanations and seemed to be listening to answer versus to hear what I was really saying/concerned about. I personally would rather see Dr. Deneke or someone else at my next visit.

Date

Aug 01, 2025
5 out of 5

Comment

Dr. Deneke is a wonderful, caring doctor

Date

Jul 12, 2025
4.8 out of 5

Comment

Very good

Date

Jun 23, 2025
5 out of 5

Comment

Goood

Date

Jun 11, 2025
5 out of 5

Comment

Dr. Deneke is a wonderful caring doctor

Date

Apr 25, 2025
5 out of 5

Comment

Good

Date

Apr 24, 2025

Make an Appointment With Dr. Deneke

New patients can make an appointment by contacting the clinic directly.

Existing patients also have the option of requesting an appointment online through UAMS Health MyChart.

UAMS Health LogoUAMS HealthUniversity of Arkansas for Medical Sciences
Mailing Address: 4301 West Markham Street, Little Rock, AR 72205
Phone: (501) 686-7000
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