POEMS Syndrome

POEMS Syndrom at UAMS

POEMS Syndrome is an extremely rare blood disorder. This disorder is so rare that many doctors misdiagnose it as multiple myeloma. At UAMS, our highly skilled and experienced doctors are able to help and treat patients who have POEMS syndrome.

POEMS is an acronym for the five main aspects of this disease:

  • Polyneuropathy – nerve symptoms such as numbness, tingling or weakness of hands and feet
  • Organomegaly – enlarged organs, usually the liver, spleen or lymph nodes
  • Endocrinopathy – changes in hormone production
  • Monoclonal gammopathy – abnormal blood protein cells
  • Skin defects – increased skin pigment, increased body hair on face, limbs and chest, skin thickening or swelling

Not all of these symptoms have to be present for you to have POEMS Syndrome. The two most common features are polyneuropathy and monoclonal gammopathy. Most of the people who have this syndrome are more than 50 years old, and the cause of POEMS syndrome is unknown.

Our caring doctors at UAMS can offer you personalized treatment for POEMS. Treatment will depend on the stage and severity of your condition and your individual symptoms. Some of the treatments can include:

  • Radiation therapy
  • Corticosteroids
  • Chemotherapy
  • Bone marrow transplant
  • Hormone replacement therapy
  • Physical therapy

Our compassionate staff can help you. Please contact us for more information about how we treat patients with POEMS Syndrome.

Learn more about the UAMS Myeloma Institute for Research and Therapy.