• Skip to primary navigation
  • Skip to main content
  • Skip to primary navigation
  • Skip to main content
Choose which site to search.
UAMS Health Logo UAMS Health
  • UAMS.edu
  • MyChart
  • Giving
  • Emergency Room
  • Types of Care
  • Locations
  • Doctors
  • Patients and Guests
  • Referring Physicians
  • Appointments
  • About Us
    • Awards and Recognition
    • Clinical Trials
  1. UAMS Health
  2. Hepatitis B Vaccine

Hepatitis B Vaccine

Why get vaccinated?

Hepatitis B vaccine can prevent hepatitis B. Hepatitis B is a liver disease that can cause mild illness lasting a few weeks, or it can lead to a serious, lifelong illness.

  • Acute hepatitis B infection is a short-term illness that can lead to fever, fatigue, loss of appetite, nausea, vomiting, jaundice (yellow skin or eyes, dark urine, clay-colored bowel movements), and pain in the muscles, joints, and stomach.
  • Chronic hepatitis B infection is a long-term illness that occurs when the hepatitis B virus remains in a person’s body. Most people who go on to develop chronic hepatitis B do not have symptoms, but it is still very serious and can lead to liver damage (cirrhosis), liver cancer, and death. Chronically-infected people can spread hepatitis B virus to others, even if they do not feel or look sick themselves.

Hepatitis B is spread when blood, semen, or other body fluid infected with the hepatitis B virus enters the body of a person who is not infected. People can become infected through:

  • Birth (if a mother has hepatitis B, her baby can become infected)
  • Sharing items such as razors or toothbrushes with an infected person
  • Contact with the blood or open sores of an infected person
  • Sex with an infected partner
  • Sharing needles, syringes, or other drug-injection equipment
  • Exposure to blood from needlesticks or other sharp

Most people who are vaccinated with hepatitis B vaccine are immune for life.

Hepatitis B vaccine

Hepatitis B vaccine is usually given as 2, 3, or 4 shots.

Infants should get their first dose of hepatitis B vaccine at birth and will usually complete the series at 6 months of age (sometimes it will take longer than 6 months to complete the series).

Children and adolescents younger than 19 years of age who have not yet gotten the vaccine should also be vaccinated.

Hepatitis B vaccine is also recommended for certain unvaccinated adults:

  • People whose sex partners have hepatitis B
  • Sexually active persons who are not in a long-term monogamous relationship
  • Persons seeking evaluation or treatment for a sexually transmitted disease
  • Men who have sexual contact with other men
  • People who share needles, syringes, or other drug-injection equipment
  • People who have household contact with someone infected with the hepatitis B virus
  • Health care and public safety workers at risk for exposure to blood or body fluids
  • Residents and staff of facilities for developmentally disabled persons
  • Persons in correctional facilities
  • Victims of sexual assault or abuse
  • Travelers to regions with increased rates of hepatitis B
  • People with chronic liver disease, kidney disease, HIV infection, infection with hepatitis C, or diabetes
  • Anyone who wants to be protected from hepatitis B

Hepatitis B vaccine may be given at the same time as other vaccines.

UAMS Health LogoUAMS HealthUniversity of Arkansas for Medical Sciences
Mailing Address: 4301 West Markham Street, Little Rock, AR 72205
Phone: (501) 686-7000
  • Facebook
  • X
  • Instagram
  • YouTube
  • LinkedIn
  • Pinterest
  • Disclaimer
  • Terms of Use
  • Privacy Statement
  • Notice of Privacy Practices
  • Price Transparency
  • Legal Notices

© 2025 University of Arkansas for Medical Sciences